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To bypass the pharmacological challenges associated with unspecific blocking of NMDA receptors, we designed a peptidedrug conjugate comprising the NMDA receptor antagonist MK-801 and a GLP-1 peptide analogue

GLP-1 drugs have been extensively studied and are known to be effective across a wide range of patients, including those with diabetes and obesity

Tirzepatide (Zepbound) How it works : Tirzepatide is unique because it activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, offering dual action for weight loss and metabolic improvement

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